Nineteen of Medvedev's twenty-one titles have been won on hard surfaces
A comeback the Russian player claimed his initial trophy for 882 days with success over Corentin Moutet in the competition final.
The athlete, a former number one, has had a challenging period, managing just a single victory at the big events and experiencing a meltdown at the New York tournament.
The player's inconsistency on the tennis tour - and difficulties with his serve in especial - caused him falling of the world's top 10 and eventually splitting with former trainer his previous coach.
Currently training with his coach and Goetzke, the tennis star has steadily advanced in the last few weeks - culminating in a hard-fought 7-5 4-6 6-3 triumph over Frenchman Moutet.
It is Medvedev's first championship following the Rome competition and initial on a hard surface from spring of that year.
Victory also signifies the Russian has won 21 victories at twenty-one different events.
"This marks the first occasion I have attended a event with my children at once, so to get a trophy is really nice," commented tennis professional Medvedev.
"This championship is in honour of my second daughter my daughter, because the maiden victory I won when my older daughter my daughter was born was for her."
The athlete, the former major winner, had been defeated in his past six finals, comprising in Halle earlier this year.
Medvedev's defensive approach and frequent emotional displays on court had led some to question if his capacity to perform at the top level was over.
However the 29-year-old has implemented adjustments in the last few weeks, making an effort to come to the net and compete positively, reinforced by an improved serving game.
He came back from a deficit in the opening set against the difficult opponent, winning four of the last five games to go ahead.
The competitors traded breaks in the second set before Moutet, bidding for his maiden ATP Tour title, took control to create a decider.
He rescued four initial opportunities in a competitive third set before Medvedev broke to that score to serve for the match.
Appropriately, he secured the title with a point at the net, with the Frenchman unable to control a return after a lengthy match.